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Invertebrate Cytokines and the Phylogeny of Immunity : Facts and Paradoxes book

Invertebrate Cytokines and the Phylogeny of Immunity : Facts and Paradoxes book

Invertebrate Cytokines and the Phylogeny of Immunity : Facts and Paradoxes by Alain Beschin

Invertebrate Cytokines and the Phylogeny of Immunity : Facts and Paradoxes
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Author: Alain Beschin
Number of Pages: 195 pages
Published Date: 22 Nov 2012
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Publication Country: Berlin, Germany
Language: English
ISBN: 9783642622366
File Name: invertebrate.cytokines.and.the.phylogeny.of.immunity.facts.and.paradoxes.pdf
Download Link: invertebrate cytokines and the phylogeny of immunity facts and paradoxes
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Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated. In the present book, recent studies demonstrating cytokine-like activities and related signaling pathways in invertebrates are critically reviewed, focusing on findings from molecular biology and taking advantage of the completion of the genome from the fly Drosophila and the worm Caenorhabditis elegans.

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